⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405315 | 0.85 | MEN1 (0.61) | — | |
| Hydrochloric Acid SCHEMBL8742967 | 0.82 | MEN1 (0.58) | — | |
| SCHEMBL1268031 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL28298378 | 0.78 | — | — | |
| SCHEMBL27948307 | 0.76 | — | — | |
| SCHEMBL406586 | 0.76 | — | — | |
| SCHEMBL7534423 | 0.76 | — | — | |
| SCHEMBL27370986 | 0.76 | — | — | |
| SCHEMBL2227737 | 0.76 | — | — | |
| SCHEMBL19418969 | 0.74 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483316-A | 5-acetic acid-1-(6-bromopyridine)-1 hydrogen-pyrazole-3-methyl acetate and synthesis method thereof | UNIV GUILIN TECH GUT | 2014-01-01 | — | — | CN | claimed |
| CN-101643446-A | Method for preparing 2-amino-6-chloropyridine | ENJIANG XIA | 2010-02-10 | — | — | CN | claimed |
| EP-0930300-B1 | Process for preparing (poly)chloropyridines | DAICEL CHEM (JP) | 2003-01-22 | — | — | EP | claimed |
| US-5977370-A | Process for preparing pyridine chloride | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | claimed |
| EP-0930300-A1 | Process for preparing (poly)chloropyridines | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 1999-07-21 | — | — | EP | claimed |
| JP-11180956-A | — | — | None | — | — | JP | disclosed |
| CN-109438487-A | Double fluorine boron hyperfluorescence dyestuffs of acyl pyridine hydrazine and preparation method thereof | 安徽师范大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-109400625-A | Condensed-bicyclic class compound and its application in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-102725290-B | As the condensed heterocyclic compouds of ion channel modulators | GILEAD SCIENCES, INC. (US) | 2016-03-09 | — | — | CN | disclosed |
| CN-103483316-A | 5-acetic acid-1-(6-bromopyridine)-1 hydrogen-pyrazole-3-methyl acetate and synthesis method thereof | UNIV GUILIN TECH GUT | 2014-01-01 | — | — | CN | disclosed |
| CN-102414194-A | Soluble guanylate cyclase activators | MERCK SHARP & DOHME | 2012-04-11 | — | — | CN | disclosed |
| CN-101939053-A | Soluble guanylate cyclase activators | MERCK SHARP & DOHME | 2011-01-05 | — | — | CN | disclosed |
| CN-101679405-A | 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC | 2010-03-24 | — | — | CN | disclosed |
| CN-101643446-A | Method for preparing 2-amino-6-chloropyridine | ENJIANG XIA | 2010-02-10 | — | — | CN | disclosed |
| EP-0930300-B1 | Process for preparing (poly)chloropyridines | DAICEL CHEM (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5977370-A | Process for preparing pyridine chloride | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5977370-A | Process for preparing pyridine chloride | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0930300-A1 | Process for preparing (poly)chloropyridines | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0930300-A1 | Process for preparing (poly)chloropyridines | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
| JP-H11180956-A | PRODUCTION OF PYRIDINE CHLORIDE | DAICEL CHEM IND LTD | 1999-07-06 | — | — | JP | disclosed |