Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7026436 | 0.99 | CACNA1C (0.65) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| SCHEMBL7022579 | 0.88 | CACNA1C (0.52) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL7025520 | 0.87 | CACNA1C (0.51) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL7024465 | 0.85 | CACNA1C (0.68) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| SCHEMBL8055937 | 0.82 | CACNA1C (0.67) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| SCHEMBL7025437 | 0.81 | LTA4H (0.48) | CACNA1CMAPTSMN1; SMN2LTA4HALDH1A1 | |
| Hydrochloric Acid SCHEMBL7024049 | 0.80 | CACNA1C (0.67) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| SCHEMBL742344 | 0.80 | CACNA1C (1.00) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| SCHEMBL29447128 | 0.80 | CACNA1C (1.00) | CACNA1CMAPTLMNAL3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL7026665 | 0.80 | LTA4H (0.47) | CACNA1CMAPTSMN1; SMN2LTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031556-B1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6162832-A | 2-Phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO., INC. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-1031556-A1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-08-30 | — | — | EP | disclosed |