Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.67 |
| ▸ | NQO2 | P16083 | 4/20 | 0.67 |
| ▸ | SPR | P35270 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343419 | 0.86 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2SPR | |
| SCHEMBL7099888 | 0.83 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5340374 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6214122 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5341366 | 0.80 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2SPR | |
| SCHEMBL5338799 | 0.80 | NQO2 (0.67) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5337441 | 0.79 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2SPR | |
| SCHEMBL3814109 | 0.78 | MTNR1A (0.68) | MTNR1AMTNR1B | |
| SCHEMBL7099796 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5341459 | 0.78 | NQO2 (0.74) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |