Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.76 |
| ▸ | RORC | P51449 | 3/20 | 0.71 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | FADS1 | O60427 | 3/20 | 0.52 |
| ▸ | MLYCD | O95822 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963068 | 0.87 | PTGS1 (1.00) | PTGS1P2RX1SMN1; SMN2FADS1NPC1 | |
| SCHEMBL12334586 | 0.84 | RORC (0.72) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL31078214 | 0.83 | RORC (0.71) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL31078114 | 0.83 | RORC (1.00) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL31078465 | 0.83 | RORC (0.71) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL12334368 | 0.83 | RORC (1.00) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL12334371 | 0.83 | SMN1; SMN2 (0.76) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL31078101 | 0.83 | SMN1; SMN2 (0.76) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL12334663 | 0.83 | RORC (0.71) | PTGS1RORCSMN1; SMN2MLYCDNPC1 | |
| SCHEMBL12334373 | 0.83 | RORC (0.71) | PTGS1RORCSMN1; SMN2MLYCDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |