Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 0.94 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.94 |
| ▸ | NQO2 | P16083 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014411 | 0.97 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7021698 | 0.92 | MTNR1A (0.80) | MTNR1AMTNR1B | |
| SCHEMBL7020913 | 0.92 | MTNR1A (0.83) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7016687 | 0.91 | MTNR1A (0.82) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7018268 | 0.89 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7016566 | 0.87 | MTNR1A (0.91) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7016806 | 0.86 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7017352 | 0.86 | MTNR1A (0.93) | MTNR1AMTNR1B | |
| SCHEMBL7015269 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7017361 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | claimed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | claimed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | claimed |
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| JP-2001011035-A | NEW SUBSTITUTED DIMERIC COMPOUND, ITS PRODUCTION, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ADIR | 2001-01-16 | — | — | JP | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |