SCHEMBL7019293

SCHEMBL7019293

CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4scc(CCNC(C)=O)c4c3)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 20/20 1.00
MTNR1B P49286 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7016626 0.98 MTNR1A (0.96) MTNR1AMTNR1B
SCHEMBL7015784 0.91 MTNR1A (0.87) MTNR1AMTNR1B
SCHEMBL7015269 0.89 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7021229 0.88 MTNR1A (0.79) MTNR1AMTNR1B
SCHEMBL7014169 0.88 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7015929 0.88 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7019176 0.88 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7013672 0.88 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7017361 0.87 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7018268 0.86 MTNR1A (1.00) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1057826-B1 Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-04-16 EP claimed
US-6310074-B1 TREATING MELATONINERGIC DISORDERS ADIR ET COMPAGNIE (FR) 2001-10-30 US claimed
EP-1057826-A1 Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2000-12-06 EP claimed
EP-1057826-B1 Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-04-16 EP disclosed
US-6310074-B1 TREATING MELATONINERGIC DISORDERS ADIR ET COMPAGNIE (FR) 2001-10-30 US disclosed
EP-1057826-A1 Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2000-12-06 EP disclosed