Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019474 | 1.00 | MAPT (0.54) | MAPTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL7021126 | 0.90 | MAPT (0.55) | MAPTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL7021124 | 0.90 | MAPT (0.55) | MAPTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL6030677 | 0.86 | MAPT (0.52) | MAPTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL13184597 | 0.79 | CTSK (0.53) | MAPTCTSKCTSSPPARAMMP2 | |
| SCHEMBL19312076 | 0.79 | CTSK (0.53) | MAPTCTSKCTSSPPARAMMP2 | |
| SCHEMBL7754157 | 0.79 | CTSK (0.53) | MAPTCTSKCTSSPPARAMMP2 | |
| SCHEMBL23200660 | 0.78 | MAPT (0.52) | MAPTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL13921179 | 0.78 | MAPT (0.54) | MAPTSYKLMNASMN1; SMN2CTSK | |
| SCHEMBL4493086 | 0.78 | MAPT (0.54) | MAPTSYKLMNASMN1; SMN2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |