Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013922 | 0.85 | KMT2A (0.43) | MTNR1BKMT2APOLBLMNATP53 | |
| SCHEMBL7015364 | 0.84 | TRPV1 (0.43) | TRPV1KMT2ALMNANPC1MAPK1 | |
| SCHEMBL7019000 | 0.84 | TRPV1 (0.45) | TRPV1KMT2ALMNAMAPK1KDM4E | |
| SCHEMBL7011306 | 0.80 | TRPV1 (0.45) | TRPV1KMT2ALMNATP53NPSR1 | |
| SCHEMBL7016543 | 0.78 | SMN1; SMN2 (0.56) | MTNR1BKMT2APOLBLMNATP53 | |
| SCHEMBL7016269 | 0.76 | PTGIR (0.45) | MTNR1BKMT2ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7020328 | 0.76 | TRPV1 (0.45) | TRPV1KMT2ALMNATP53NPC1 | |
| SCHEMBL7017831 | 0.74 | NPC1 (0.48) | MTNR1BKMT2APOLBLMNANPC1 | |
| SCHEMBL21268155 | 0.73 | ALDH1A1 (0.39) | KMT2APOLBLMNANPC1MAPK1 | |
| SCHEMBL7016251 | 0.73 | KMT2A (0.41) | KMT2APOLBLMNATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |