Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027704 | 0.90 | ALOX15 (0.38) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL20610516 | 0.83 | ALOX15 (0.49) | ALOX15ALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL1844934 | 0.83 | ALOX15 (0.49) | ALOX15ALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL441627 | 0.80 | ALOX15 (0.44) | ALOX15ALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL14565294 | 0.80 | ALOX15 (0.44) | ALOX15ALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL24459467 | 0.80 | ALOX15 (0.44) | ALOX15ALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL8758503 | 0.80 | ALOX15 (0.36) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL9385664 | 0.79 | ALOX15 (0.38) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL28509566 | 0.77 | ALOX15 (0.39) | ALOX15ALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL1774018 | 0.75 | ALOX15 (0.42) | ALOX15ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911315-A1 | Beta-ketoester | Givaudan Roure (International) S.A. (CH) | 1999-04-28 | — | — | EP | claimed |
| EP-0911315-B1 | Beta-ketoester | GIVAUDAN SA (CH) | 2003-06-11 | — | — | EP | disclosed |
| US-6348618-B1 | PREPARING ORGANOLEPTIC OR ANTIMICROBIAL COMPOUNDS BY CONTACTING BETA-KETO ESTER WITH MATERIAL SELECTED FROM BACTERIA, ENZYMES, AND MATERIAL HAVING ACIDIC OR ALKALINE PH, ELEVATING TEMPERATURE, EXPOSING TO LIGHT | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2002-02-19 | — | — | US | disclosed |
| US-6222062-B1 | USEFUL AS PRECURSORS FOR ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES AND MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2001-04-24 | — | — | US | disclosed |
| EP-1090624-A2 | Beta ketoester | Givaudan SA (CH) | 2001-04-11 | — | — | EP | disclosed |
| EP-0911315-A1 | Beta-ketoester | Givaudan Roure (International) S.A. (CH) | 1999-04-28 | — | — | EP | disclosed |