Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407634 | 0.88 | TSHR (0.45) | POLBHTTCYP19A1TSHRALDH1A1 | |
| SCHEMBL7013539 | 0.86 | TSHR (0.52) | POLBHTTCYP19A1TSHR | |
| SCHEMBL7465368 | 0.84 | CYP19A1 (0.41) | POLBHTTCYP19A1TSHRALDH1A1 | |
| SCHEMBL11273785 | 0.82 | CYP19A1 (0.50) | POLBHTTCYP19A1TSHRALDH1A1 | |
| SCHEMBL787701 | 0.81 | GAA (0.38) | POLBTSHRALDH1A1HPGDIDO1 | |
| SCHEMBL18407594 | 0.81 | CYP19A1 (0.32) | POLBHTTCYP19A1ALDH1A1HPGD | |
| SCHEMBL5005099 | 0.80 | POLB (0.52) | POLBHTTALDH1A1HPGD | |
| SCHEMBL18538952 | 0.80 | HTT (0.47) | POLBHTTCYP19A1TSHRIDO1 | |
| SCHEMBL20511401 | 0.79 | TSHR (0.54) | POLBHTTCYP19A1TSHRALDH1A1 | |
| SCHEMBL1827937 | 0.78 | IDO1 (0.58) | CYP19A1TSHRALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |