Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148836 | 0.92 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7016937 | 0.91 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7012987 | 0.90 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7020137 | 0.90 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7022828 | 0.90 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7023261 | 0.89 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7025946 | 0.89 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7018096 | 0.89 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7017650 | 0.89 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7017360 | 0.88 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |