SCHEMBL7019940

SCHEMBL7019940

CC[Si](CC)(CC)O[Si](CC)(CC)CC.OCCCCCI

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4816226 0.77 LMNA (0.42) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4536697 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4529900 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4526908 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4532638 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4538832 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2092969 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL180040 0.75
SCHEMBL4533125 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4528548 0.75 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789022-B1 Difluoroprostacyclins, intermediates for production thereof and processes for production thereof ASAHI GLASS CO LTD (JP) 2003-06-18 EP disclosed
EP-0669329-B1 Difluorprostacyclins, intermediates for production thereof and processes for production thereof ASAHI GLASS CO LTD (JP) 1998-05-20 EP disclosed
US-5747531-A STABILITY; ANTICOAGULANTS, VASODILATORS ASAHI GLASS COMPANY LTD. (JP) 1998-05-05 US disclosed
EP-0789022-A1 Difluoroprostacyclins, intermediates for production thereof and process for production ASAHI GLASS COMPANY LTD. (JP) 1997-08-13 EP disclosed
US-5616732-A Intermediates for difluoroprostacyclins and methods for their production ASAHI GLASS COMPANY LTD. (JP) 1997-04-01 US disclosed
US-5538995-A Difluoroprostacyclins ASAHI GLASS COMPANY LTD. (JP) 1996-07-23 US disclosed
EP-0669329-A1 Difluorprostacyclins, intermediates for production thereof and processes for production thereof ASAHI GLASS COMPANY LTD. (JP) 1995-08-30 EP disclosed