Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FABP7 | O15540 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482370 | 0.86 | TSHR (0.45) | BACE1TSHRGAAFABP7FABP5 | |
| SCHEMBL16124528 | 0.86 | TSHR (0.50) | TSHRGAAHTR2CHTR2BKDM4E | |
| SCHEMBL29010886 | 0.86 | TSHR (0.47) | TSHRGAAFABP7FABP5HTR2C | |
| SCHEMBL29011009 | 0.86 | TSHR (0.50) | TSHRGAAHTR2CHTR2BKDM4E | |
| SCHEMBL693351 | 0.85 | TSHR (0.63) | BACE1TSHRGAAFABP7FABP5 | |
| SCHEMBL4069956 | 0.85 | TSHR (0.63) | BACE1TSHRGAAFABP7FABP5 | |
| SCHEMBL630517 | 0.85 | TSHR (0.63) | BACE1TSHRGAAFABP7FABP5 | |
| SCHEMBL13416434 | 0.84 | TSHR (0.46) | BACE1TSHRGAAHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1000787 | 0.84 | TSHR (0.65) | BACE1TSHRGAAFABP7FABP5 | |
| Hydrochloric Acid SCHEMBL693350 | 0.84 | TSHR (0.65) | BACE1TSHRGAAFABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307455-A2 | INHIBITORS OF ALPHA-L BETA-2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001030781-A2 | INHIBITORS OF αLβ2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |