Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702032 | 1.00 | OPRL1 (0.56) | OPRL1CHRM4DRD4USP2OPRM1 | |
| SCHEMBL3441693 | 0.88 | OPRL1 (0.51) | OPRL1CHRM4DRD4USP2OPRM1 | |
| SCHEMBL3441694 | 0.88 | OPRL1 (0.51) | OPRL1CHRM4DRD4USP2OPRM1 | |
| SCHEMBL701015 | 0.85 | OPRL1 (0.59) | OPRL1CHRM4DRD4USP2OPRM1 | |
| SCHEMBL3126554 | 0.81 | OPRL1 (0.62) | OPRL1CHRM4DRD4USP2OPRM1 | |
| SCHEMBL3136902 | 0.79 | OPRL1 (0.86) | OPRL1CHRM4DRD4OPRM1LMNA | |
| SCHEMBL3124201 | 0.79 | OPRL1 (0.60) | OPRL1CHRM4DRD4USP2OPRM1 | |
| SCHEMBL12473468 | 0.78 | ALDH1A1 (0.43) | OPRL1OPRM1LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4813917 | 0.78 | OPRL1 (0.84) | OPRL1CHRM4DRD4OPRM1LMNA | |
| SCHEMBL699951 | 0.78 | OPRL1 (0.63) | OPRL1CHRM4DRD4USP2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264407-A1 | Substituted Sulfonamide Compounds | CNR1, SUCNR1, OPRL1 | OPRL1 3/4885CHRM4 997/4885DRD4 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.