Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 14/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 12/20 | 0.67 |
| ▸ | LCK | P06239 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024758 | 0.90 | MKNK1 (0.70) | MKNK1MKNK2LCK | |
| SCHEMBL7022907 | 0.85 | LCK (0.70) | MKNK1MKNK2LCK | |
| SCHEMBL7020088 | 0.83 | LCK (0.70) | MKNK1MKNK2LCK | |
| SCHEMBL7027192 | 0.83 | LCK (0.70) | MKNK1MKNK2LCK | |
| SCHEMBL7025386 | 0.83 | LCK (0.70) | MKNK1MKNK2LCK | |
| SCHEMBL7024872 | 0.82 | LCK (0.77) | MKNK1MKNK2LCK | |
| SCHEMBL7023275 | 0.82 | LCK (0.69) | MKNK1MKNK2LCK | |
| SCHEMBL18803629 | 0.81 | MKNK1 (1.00) | MKNK1MKNK2LCK | |
| SCHEMBL7020797 | 0.80 | LCK (0.66) | MKNK1MKNK2LCK | |
| SCHEMBL7022617 | 0.80 | LCK (1.00) | MKNK1MKNK2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206265-B1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2003-11-12 | — | — | EP | disclosed |
| US-6498165-B1 | PYRIMIDINE COMPOUNDS; PROPHYLAXIS AND TREATMENT OF SUCH AS IMMUNE DISEASES, HYPERPROLIFERATIVE DISORDERS, CANCER, ANGIOGENSIS, ATHEROSCELEROSIS, GRAFT REJECTION, RHEUMATOID ARTHRITIS, PSORIASIS | MERCK & CO., INC. | 2002-12-24 | — | — | US | disclosed |