Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017894 | 0.85 | PARP1 (0.48) | PARP1PARP2KCNH2 | |
| SCHEMBL7017660 | 0.85 | PARP1 (0.60) | PARP1PARP2KCNH2 | |
| SCHEMBL7017391 | 0.83 | PARP1 (0.47) | PARP1PARP2KCNH2 | |
| Hydrochloric Acid SCHEMBL7018458 | 0.82 | PARP1 (0.55) | PARP1PARP2 | |
| SCHEMBL7016636 | 0.80 | PARP1 (0.51) | PARP1PARP2KCNH2 | |
| SCHEMBL7023422 | 0.80 | PARP1 (0.46) | PARP1PARP2 | |
| SCHEMBL7018142 | 0.80 | PARP1 (0.47) | PARP1PARP2KCNH2 | |
| SCHEMBL4331151 | 0.78 | PARP1 (0.62) | PARP1PARP2KCNH2 | |
| Hydrochloric Acid SCHEMBL7019654 | 0.78 | PARP1 (0.51) | PARP1PARP2KCNH2 | |
| SCHEMBL6793333 | 0.77 | PARP1 (0.74) | PARP1PARP2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355888-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002048117-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-20 | — | — | WO | disclosed |