Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023192 | 0.84 | PARP1 (0.49) | PARP1PARP2KCNH2 | |
| SCHEMBL7017894 | 0.83 | PARP1 (0.48) | PARP1PARP2KCNH2 | |
| SCHEMBL7017660 | 0.83 | PARP1 (0.60) | PARP1PARP2KCNH2 | |
| SCHEMBL6795963 | 0.81 | PARP1 (0.76) | PARP1PARP2KCNH2 | |
| SCHEMBL7017391 | 0.81 | PARP1 (0.47) | PARP1PARP2KCNH2 | |
| SCHEMBL7020655 | 0.80 | PARP1 (0.45) | PARP1PARP2KCNH2 | |
| Hydrochloric Acid SCHEMBL7018458 | 0.80 | PARP1 (0.55) | PARP1PARP2 | |
| SCHEMBL7018142 | 0.80 | PARP1 (0.47) | PARP1PARP2KCNH2 | |
| SCHEMBL7023422 | 0.80 | PARP1 (0.46) | PARP1PARP2 | |
| SCHEMBL6650044 | 0.79 | PARP1 (0.51) | PARP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355888-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002048117-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-20 | — | — | WO | disclosed |