Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 17/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015198 | 0.92 | TDP1 (0.48) | TDP1CYP3A4 | |
| SCHEMBL9015373 | 0.83 | TDP1 (0.48) | TDP1CYP3A4 | |
| SCHEMBL9943757 | 0.80 | CYP3A4 (0.46) | TDP1CYP3A4 | |
| SCHEMBL19286627 | 0.78 | CYP3A4 (0.57) | TDP1CYP3A4 | |
| SCHEMBL893784 | 0.78 | CYP3A4 (0.57) | TDP1CYP3A4 | |
| SCHEMBL7021692 | 0.77 | TDP1 (0.48) | TDP1CYP3A4 | |
| SCHEMBL2919212 | 0.77 | TDP1 (0.50) | TDP1CYP3A4 | |
| SCHEMBL29961611 | 0.72 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL12249326 | 0.72 | CYP3A4 (0.66) | CYP3A4 | |
| SCHEMBL14124342 | 0.70 | TDP1 (0.54) | TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003530310-A | — | — | 2003-10-14 | — | — | JP | claimed |
| EP-1227797-A2 | SOLID DISPERSION PHARMACEUTICAL FORMULATIONS | ABBOTT LABORATORIES (US) | 2002-08-07 | — | — | EP | claimed |
| WO-2001034118-A2 | SOLID DISPERSION PHARMACEUTICAL FORMULATIONS | ABBOTT LABORATORIES (US) | 2001-05-17 | — | — | WO | claimed |