Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000972 | 0.81 | — | — | |
| SCHEMBL394730 | 0.81 | F2 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL9172412 | 0.79 | F2 (0.55) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL242874 | 0.75 | F2 (0.38) | F2PRSS1PRSS2PRSS3CA1 | |
| Lithium Ion SCHEMBL1248473 | 0.73 | F2 (0.36) | F2PRSS1PRSS2PRSS3CA1 | |
| Lithium Ion SCHEMBL3153428 | 0.69 | F2 (0.39) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL16140083 | 0.67 | F2 (0.32) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL1513007 | 0.65 | — | — | |
| SCHEMBL778180 | 0.65 | CA2 (0.39) | CA1CA2CA7CA13 | |
| SCHEMBL776245 | 0.63 | CA2 (0.44) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |