SCHEMBL7022129

SCHEMBL7022129

CCOC(=O)C(Cc1ccc(OCc2ccc(COc3ccc(CC(OCC)C(=O)O)cc3)cc2)cc1)OCC

nearest known ligand 0.87

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.87
PPARG P37231 12/20 0.75
PPARD Q03181 11/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7023381 0.95 PPARA (0.76) PPARAPPARGPPARD
SCHEMBL15811673 0.92 PPARA (0.75) PPARAPPARGPPARD
SCHEMBL5338861 0.92 PPARA (0.75) PPARAPPARGPPARD
SCHEMBL4758109 0.92 PPARA (0.75) PPARAPPARGPPARD
Hydrochloric Acid SCHEMBL7212899 0.91 PPARA (0.73) PPARAPPARGPPARD
Hydrochloric Acid SCHEMBL7212895 0.91 PPARA (0.73) PPARAPPARGPPARD
SCHEMBL16415813 0.89 PPARA (0.92) PPARAPPARGPPARD
SCHEMBL5993963 0.89 PPARA (0.92) PPARAPPARGPPARD
SCHEMBL5608022 0.89 PPARA (0.92) PPARAPPARGPPARD
SCHEMBL7211456 0.89 PPARA (0.70) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1276710-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2003-01-22 EP claimed
US-6509374-B2 For therapy of conditinos mediated by Peroxisome Proliferator-Activated Receptors (PPAR) such as diabetes and obesity NOVO NORDISK A/S (DK) 2003-01-21 US claimed
US-20020022656-A1 New compounds, their preparation and use NOVO NORDISK A/S (DK) 2002-02-21 US claimed
WO-2001079150-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-10-25 WO claimed
EP-1276710-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2003-01-22 EP disclosed
US-6509374-B2 For therapy of conditinos mediated by Peroxisome Proliferator-Activated Receptors (PPAR) such as diabetes and obesity NOVO NORDISK A/S (DK) 2003-01-21 US disclosed
US-20020022656-A1 New compounds, their preparation and use NOVO NORDISK A/S (DK) 2002-02-21 US disclosed
WO-2001079150-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020022656-A1 New compounds, their preparation and use PPARG, PPARD, PPARA PPARA 3/4885PPARG 1/4885PPARD 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.