Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | SDCBP | O00560 | 1/20 | 0.40 |
| ▸ | SDC2 | P34741 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925641 | 0.80 | GRM2 (0.44) | GRM2L3MBTL1ATRHPNNAMPT | |
| SCHEMBL20770858 | 0.80 | GRM2 (0.46) | GRM2L3MBTL1ATRHPNNAMPT | |
| SCHEMBL30686742 | 0.79 | NAMPT (0.46) | GRM2L3MBTL1ATRNAMPTHDAC1 | |
| SCHEMBL26942761 | 0.79 | NAMPT (0.46) | GRM2L3MBTL1ATRNAMPTHDAC1 | |
| SCHEMBL18664387 | 0.76 | HDAC1 (0.53) | GRM2L3MBTL1ATRHPNNAMPT | |
| SCHEMBL10264861 | 0.75 | L3MBTL1 (0.51) | L3MBTL1NAMPTHDAC1DYRK1AGAA | |
| SCHEMBL3180689 | 0.75 | L3MBTL1 (0.61) | L3MBTL1NAMPTHDAC1CA1CA2 | |
| SCHEMBL30625710 | 0.75 | L3MBTL1 (0.51) | L3MBTL1NAMPTHDAC1DYRK1AGAA | |
| SCHEMBL359537 | 0.74 | GAA (0.52) | GRM2L3MBTL1HPNNAMPTHDAC1 | |
| SCHEMBL54834 | 0.74 | EPHX2 (0.55) | L3MBTL1NAMPTHDAC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302463-A1 | MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |