Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 13/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027521 | 0.87 | F2 (0.40) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7022361 | 0.86 | TPSAB1 (0.40) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7024445 | 0.81 | F2 (0.45) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7022726 | 0.80 | F2 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7027523 | 0.79 | F2 (0.39) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7016138 | 0.78 | TPSAB1 (0.41) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7016094 | 0.78 | F2 (0.39) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7016098 | 0.76 | F2 (0.42) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021982 | 0.75 | TPSAB1 (0.45) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7029481 | 0.74 | F2 (0.46) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |