Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13937723 | 0.72 | HMGCR (0.41) | — | |
| SCHEMBL7024357 | 0.69 | HMGCR (0.38) | — | |
| SCHEMBL7023519 | 0.69 | CYP2C19 (0.33) | — | |
| SCHEMBL16178924 | 0.68 | CDC25B (0.50) | — | |
| SCHEMBL9960161 | 0.67 | HMGCR (0.38) | — | |
| SCHEMBL19178025 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL10298961 | 0.65 | CYP2C19 (0.35) | — | |
| SCHEMBL7033924 | 0.65 | HMGCR (0.31) | — | |
| SCHEMBL7025249 | 0.64 | CYP2C19 (0.35) | — | |
| SCHEMBL7032917 | 0.64 | CYP2C19 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064253-B1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | disclosed |
| US-6346633-B1 | TERT-AMINOPHENYLESTER OF ACID | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |
| EP-1064253-A1 | ANTI-TUMOUR AGENTS | AstraZeneca AB (SE) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999048857-A1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 1999-09-30 | — | — | WO | disclosed |