Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.46 |
| ▸ | RXRG | P48443 | 4/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RARG | P13631 | 9/20 | 0.42 |
| ▸ | RARB | P10826 | 8/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 7/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478105 | 0.87 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6874738 | 0.82 | RXRA (0.67) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6032311 | 0.82 | RXRA (0.67) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6822269 | 0.82 | RXRA (0.67) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6877491 | 0.81 | RXRA (0.54) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6870456 | 0.81 | RXRA (0.49) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6870454 | 0.81 | RXRA (0.49) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6876425 | 0.80 | RXRA (0.53) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6472766 | 0.78 | RXRA (0.60) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6472771 | 0.78 | RXRA (0.60) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832081-B1 | BICYCLIC-AROMATIC COMPOUNDS | GALDERMA RECH DERMATOLOGIQUE (FR) | 2003-01-29 | — | — | EP | claimed |