Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022780 | 1.00 | CHRM2 (0.46) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL4344723 | 0.88 | CHRM2 (0.40) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL22347111 | 0.85 | MAPT (0.44) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL3168206 | 0.83 | KMT2A (0.45) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL4775413 | 0.83 | KDM4E (0.44) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL4324704 | 0.81 | KMT2A (0.43) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL1895040 | 0.80 | CHRM2 (0.41) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL6724381 | 0.80 | LDHA (0.50) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL1898134 | 0.80 | CHRM2 (0.39) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL1041725 | 0.80 | BCHE (0.44) | ADORA2AHPGDALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341792-A2 | AMIDO ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002046188-A2 | AMIDO ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |