Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027317 | 1.00 | ASAH2 (0.48) | ASAH2PRKCAMEN1CYP3A4KMT2A | |
| SCHEMBL7022930 | 1.00 | ASAH2 (0.48) | ASAH2PRKCAMEN1CYP3A4KMT2A | |
| SCHEMBL8844592 | 0.93 | F7 (0.51) | PRKCAMEN1CYP3A4KMT2AFAAH | |
| SCHEMBL28847936 | 0.87 | TSHR (0.39) | ASAH2PRKCACYP3A4USP2LMNA | |
| SCHEMBL24004659 | 0.86 | ASAH2 (0.44) | ASAH2MEN1CYP3A4KMT2AFAAH | |
| SCHEMBL15027033 | 0.85 | LMNA (0.59) | ASAH2PRKCAFAAHGMNNUSP2 | |
| SCHEMBL9997803 | 0.84 | MEN1 (0.47) | PRKCAMEN1CYP3A4KMT2AFAAH | |
| SCHEMBL9997799 | 0.84 | MEN1 (0.47) | PRKCAMEN1CYP3A4KMT2AFAAH | |
| SCHEMBL11149144 | 0.84 | USP2 (0.41) | ASAH2PRKCACYP3A4USP2LMNA | |
| SCHEMBL11149146 | 0.84 | USP2 (0.41) | ASAH2PRKCACYP3A4USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872467-B1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEM CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-5886214-A | CATALYTIC ASYMMETRIC HYDROGENATION OF ENOL ESTERS BEARING A VINYLLIC OR AN ACETYLENIC SUBSTITUENT BY USING A CHIRAL RHODIUM(I) HYDROGENATION CATALYST PREPARED FROM A SUITABLE RHODIUM SALT AND AN OPTICALLY PURE PHOSPHINE LIGAND | EASTMAN CHEMICAL COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0872467-A1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEMICAL COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |