Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | CASP1 | P29466 | 2/20 | 1.00 |
| ▸ | CASP7 | P55210 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27921549 | 0.92 | KDM4E (0.85) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL590825 | 0.86 | KDM4E (0.76) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL29785070 | 0.86 | KDM4E (0.76) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL7576024 | 0.85 | KDM4E (0.74) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL30406107 | 0.85 | KDM4E (1.00) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL2554744 | 0.85 | KDM4E (1.00) | KDM4EGLAGAAALDH1A1HPGD | |
| Ocimarin SCHEMBL23752453 | 0.85 | HSD17B3 (0.79) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL3767036 | 0.85 | HSD17B3 (1.00) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL11097084 | 0.85 | HSD17B3 (0.89) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL10795060 | 0.83 | HSD17B3 (0.86) | KDM4EGLAGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256120-B1 | PSORALEN DERIVATIVES AS NON-PEPTIDIC INHIBITORS OF CHYMOTRYPSIN-LIKE ACTIVITY OF THE IMMUNOPROTEASOME | UNIV LJUBLJANI (SI) | 2018-11-14 | — | — | EP | disclosed |
| EP-0538053-B1 | Separation and analysis | MARCONI OPTICAL COMPONENTS LTD (GB) | 2003-01-22 | — | — | EP | disclosed |
| EP-0653065-B1 | SEPARATION METHOD | MARCONI OPTICAL COMPONENTS LTD (GB) | 2002-10-30 | — | — | EP | disclosed |
| US-6225043-B1 | IMMUNOASSAY IN WHICH ONE OF THE SPECIES IS MASKED AND NOT CAPABLE OF UNDERGOING SPECIFIC BINDING UNLESS REACTED WITH ENZYME WHICH EXPOSES ANTIGENIC LIGAND | GEC-MARCONI LIMITED (GB) | 2001-05-01 | — | — | US | disclosed |
| EP-0660933-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1995017670-A1 | LABELLING | GEC-MARCONI LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| EP-0653065-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994007140-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |
| WO-1994003807-A1 | SEPARATION METHOD | GEC-MARCONI LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |
| EP-0538053-A1 | Separation and analysis | GEC-MARCONI LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |