Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.74 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.71 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.64 |
| ▸ | NQO2 | P16083 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020360 | 0.90 | MTNR1A (0.87) | MTNR1AMTNR1BNOTUMNQO2KDM4E | |
| SCHEMBL7016566 | 0.90 | MTNR1A (0.91) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7016697 | 0.88 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8135457 | 0.86 | MTNR1A (0.66) | MTNR1AMTNR1BNOTUMNQO2KDM4E | |
| SCHEMBL7015300 | 0.86 | MTNR1A (0.62) | MTNR1AMTNR1BNOTUMNQO2KDM4E | |
| SCHEMBL7017649 | 0.86 | MTNR1A (0.87) | MTNR1AMTNR1BNOTUMNQO2KDM4E | |
| SCHEMBL16923847 | 0.85 | MTNR1A (0.87) | MTNR1AMTNR1BNOTUMNQO2KDM4E | |
| SCHEMBL7015644 | 0.85 | MTNR1A (0.78) | MTNR1AMTNR1BNOTUMNQO2KDM4E | |
| SCHEMBL14907324 | 0.85 | MTNR1A (0.78) | MTNR1AMTNR1BNOTUMNQO2KDM4E | |
| SCHEMBL14907338 | 0.85 | MTNR1A (0.78) | MTNR1AMTNR1BNOTUMNQO2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | claimed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | claimed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | claimed |
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |