Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978657 | 0.80 | ALDH1A1 (0.55) | MAOBALDH1A1KMT2ATDP1POLB | |
| SCHEMBL30947812 | 0.80 | ALDH1A1 (0.55) | MAOBALDH1A1KMT2ATDP1POLB | |
| SCHEMBL981569 | 0.80 | PTPN1 (0.56) | PTPN1ALDH1A1KMT2ATDP1POLB | |
| SCHEMBL9056199 | 0.76 | ALDH1A1 (0.55) | MAOBALDH1A1MAOACYP3A4CYP2D6 | |
| SCHEMBL10991271 | 0.74 | PTPN1 (0.56) | PTPN1MAOBALDH1A1KMT2ATDP1 | |
| SCHEMBL7026584 | 0.73 | PTPN1 (0.64) | PTPN1MAOBALDH1A1KMT2ATDP1 | |
| SCHEMBL16477279 | 0.70 | MAPT (0.50) | ALDH1A1KMT2AMAPTCYP3A4RAB9A | |
| SCHEMBL11266430 | 0.69 | PTPN1 (0.56) | PTPN1MAOBALDH1A1KMT2ATDP1 | |
| SCHEMBL16982170 | 0.68 | ALDH1A1 (0.55) | MAOBALDH1A1KMT2ATDP1GAA | |
| SCHEMBL31619652 | 0.67 | PTPN1 (0.58) | PTPN1ALDH1A1KMT2ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322308-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | Durect Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028366-A9 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORP (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002028366-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |