Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 13/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023625 | 1.00 | PPARG (0.64) | PPARGSIGMAR1PPARANPC1RAB9A | |
| SCHEMBL6483928 | 0.91 | PPARG (0.68) | PPARGSIGMAR1PPARANPC1RAB9A | |
| SCHEMBL6483931 | 0.91 | PPARG (0.68) | PPARGSIGMAR1PPARANPC1RAB9A | |
| SCHEMBL6476081 | 0.89 | PPARG (0.67) | PPARGSIGMAR1PPARANPC1RAB9A | |
| SCHEMBL6477169 | 0.87 | PPARG (0.64) | PPARGSIGMAR1PPARANPC1RAB9A | |
| SCHEMBL6476868 | 0.86 | RAB9A (0.70) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6476872 | 0.86 | RAB9A (0.70) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5913753 | 0.84 | PPARG (0.61) | PPARGSIGMAR1PPARANPC1RAB9A | |
| SCHEMBL5913749 | 0.84 | PPARG (0.61) | PPARGSIGMAR1PPARANPC1RAB9A | |
| SCHEMBL6487134 | 0.84 | PPARG (0.68) | PPARGSIGMAR1PPARANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | disclosed |