SCHEMBL7023958

SCHEMBL7023958

COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(OC)nc(OC)n1

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.50
GAA P10253 2/20 0.50
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA5A P35218 1/20 0.48
CA9 Q16790 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 2/20 0.47
SLC40A1 Q9NP59 1/20 0.46
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metsulfuron-Methyl SCHEMBL9136999 0.93 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL29433235 0.93 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL29378591 0.93 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL21583 0.93 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
SCHEMBL8857839 0.93 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL21416 0.92 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL10608771 0.92 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL3789956 0.92 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL1030934 0.92 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1
Metsulfuron-Methyl SCHEMBL7576469 0.92 NPC1 (0.46) NPC1GAAKDM4EALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4383113-A PLANT GROWTH REGULATORS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-10 US claimed
EP-0007687-B1 SULFONAMIDES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING SAID SULFONAMIDES AND A METHOD FOR CONTROLLING THE GROWTH OF VEGETATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-30 EP claimed
EP-0007687-A1 Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-06 EP claimed
US-20140235444-A1 SYNERGISTIC SUPRESSION OF GRASS SEEDHEAD PRODUCTION FROM APPLICATIONS OF AMINOCYCLOPYRACHLOR AND METSULFURON DOW AGROSCIENCES LLC (US) 2014-08-21 US disclosed
US-20140235444-A1 SYNERGISTIC SUPRESSION OF GRASS SEEDHEAD PRODUCTION FROM APPLICATIONS OF AMINOCYCLOPYRACHLOR AND METSULFURON DOW AGROSCIENCES LLC (US) 2014-08-21 US disclosed
EP-0562576-B1 Process for the preparation of phenyl (1,3,5-triazin-2-yl) carbamates KUREHA CHEMICAL IND CO LTD (JP) 2003-01-22 EP disclosed
US-5380843-A Process for the preparation of phenyl (1,3,5-triazin-2-yl)carbamates KUREHA KAGAKU KOGYO K.K. (JP) 1995-01-10 US disclosed
EP-0620706-A1 TABLET FORMULATION WITH INTERNAL DESICCANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-26 EP disclosed
EP-0422026-B1 TABLET FORMULATIONS OF PESTICIDES DU PONT (US) 1994-09-07 EP disclosed
WO-1993013658-A1 TABLET FORMULATION WITH INTERNAL DESICCANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-22 WO disclosed
US-5180587-A Dibasic or tribasic organic acid, carbonate or bicarbonate, dispersant, crosslinked polyvinylpyrrolidone and wetting agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-19 US disclosed
US-4394506-A HERBICIDWS, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-19 US disclosed
US-4383113-A PLANT GROWTH REGULATORS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-10 US disclosed
US-4383113-A PLANT GROWTH REGULATORS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-10 US disclosed
EP-0007687-B1 SULFONAMIDES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING SAID SULFONAMIDES AND A METHOD FOR CONTROLLING THE GROWTH OF VEGETATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-30 EP disclosed
US-4305884-A 0-CARBONYLBENZENESULFONYL ISOCYANATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-15 US disclosed
EP-0034431-A2 2-Isocyanatosulfonylbenzoic acid esters and preparation thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-08-26 EP disclosed
EP-0030138-A1 Herbicidal sulfonamides, and compositions, preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-10 EP disclosed
US-4238621-A CARBONYLBENZENESULFONYL ISOCYANATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-12-09 US disclosed
EP-0007687-A1 Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235444-A1 SYNERGISTIC SUPRESSION OF GRASS SEEDHEAD PRODUCTION FROM APPLICATIONS OF AMINOCYCLOPYRACHLOR AND METSULFURON NOTUM, MSRB3, STS NPC1 4866/4885GAA 4414/4885KDM4E 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.