Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679006 | 1.00 | CNR2 (0.44) | CNR2CNR1HSD11B1GRM2SMN1; SMN2 | |
| SCHEMBL9152632 | 0.94 | CNR2 (0.43) | CNR2CNR1HSD11B1GRM2SMN1; SMN2 | |
| SCHEMBL9152644 | 0.94 | CNR2 (0.43) | CNR2CNR1HSD11B1GRM2SMN1; SMN2 | |
| SCHEMBL13257040 | 0.89 | HSD11B1 (0.52) | CNR2CNR1HSD11B1GRM2SMN1; SMN2 | |
| SCHEMBL3712881 | 0.83 | GRM2 (0.46) | CNR2CNR1HSD11B1GRM2SMN1; SMN2 | |
| SCHEMBL16239057 | 0.83 | GRM2 (0.46) | CNR2CNR1HSD11B1GRM2SMN1; SMN2 | |
| SCHEMBL13284759 | 0.83 | HSD11B1 (0.56) | CNR2CNR1HSD11B1POLBSPHK1 | |
| SCHEMBL3898662 | 0.82 | HSD11B1 (0.38) | CNR2CNR1HSD11B1GRM2POLB | |
| SCHEMBL3898665 | 0.82 | HSD11B1 (0.38) | CNR2CNR1HSD11B1GRM2POLB | |
| SCHEMBL23279350 | 0.79 | SMN1; SMN2 (0.44) | HSD11B1SMN1; SMN2POLBSPHK1SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |