⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367180 | 0.93 | GNAO1 (0.49) | — | |
| SCHEMBL27706384 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL15743617 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL27662480 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL10633517 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL15232418 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL5680204 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL1189178 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL11122184 | 0.91 | GNAO1 (0.51) | — | |
| SCHEMBL27841802 | 0.91 | GNAO1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536151-B1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | BOOTS CO PLC (GB) | 1994-09-14 | — | — | EP | claimed |
| US-5302720-A | Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents | THE BOOTS COMPANY (GB) | 1994-04-12 | — | — | US | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | claimed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| CN-114933613-B | Preparation of PNNP ligand, ethylene oligomerization catalyst and application thereof | 万华化学集团股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-114920866-B | Preparation method of polyolefin thermoplastic elastomer | 万华化学集团股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022256387-A1 | CATIONIC POLYMER DETECTION SYSTEM, INDICATOR WIPE PRODUCT AND METHODS THEREOF | SRFC BIO, INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| CN-114644651-A | Process for producing aryloxyphosphorylated amino acid ester compound | 中国人民解放军军事科学院军事医学研究院 | 2022-06-21 | — | — | CN | disclosed |
| CN-114026072-A | Methods of treating idiopathic pulmonary fibrosis | 北京泰德制药股份有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-114007620-A | Methods of treating pain associated with endometriosis using diaminopyrimidines | 北京泰德制药股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-114007619-A | Method for treating cough by diaminopyrimidines | 北京泰德制药股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |
| US-4585725-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0137223-A2 | Photographic image-receiving element for silver salt diffusion transfer process | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-17 | — | — | EP | disclosed |
| US-3963495-A | Image-receiving element for silver salt diffusion transfer with layer of monoacrylates or monomethacrylates of polyhydric alcohols | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-15 | — | — | US | disclosed |