Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.66 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.62 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.62 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.62 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.62 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.62 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.62 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.62 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675018 | 0.91 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9510547 | 0.91 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9858666 | 0.91 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL18877605 | 0.90 | CNR1 (0.74) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL22871621 | 0.89 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL21311906 | 0.86 | TP53 (0.72) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL28149475 | 0.85 | HDAC6 (0.78) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL28142485 | 0.85 | HDAC6 (0.78) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7264242 | 0.85 | PSMB11 (0.83) | HDAC4ENPP2DGAT2PSMB11PSMA7 | |
| SCHEMBL13510734 | 0.85 | PSMB11 (0.83) | HDAC4ENPP2DGAT2PSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277790-A2 | Nucleators for crystallizable thermoplastic polymers | Ciba SC Holding AG (CH) | 2003-01-22 | — | — | EP | claimed |
| EP-0940431-A1 | Nucleators for crystallizable thermoplastic polymers | Universität Bayreuth (DE) | 1999-09-08 | — | — | EP | claimed |
| EP-1277790-A2 | Nucleators for crystallizable thermoplastic polymers | Ciba SC Holding AG (CH) | 2003-01-22 | — | — | EP | disclosed |
| EP-0940431-A1 | Nucleators for crystallizable thermoplastic polymers | Universität Bayreuth (DE) | 1999-09-08 | — | — | EP | disclosed |