Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | PLG | P00747 | 4/20 | 0.36 |
| ▸ | PLAU | P00749 | 4/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.36 |
| ▸ | PLAT | P00750 | 3/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27477978 | 0.83 | ATM (0.41) | BCL2L1ALDH1A1HPGDHSD17B10CHRNB2 | |
| SCHEMBL17313535 | 0.83 | HDAC4 (0.39) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| Biphenyl SCHEMBL27881593 | 0.80 | HPGD (0.54) | BCL2L1ALDH1A1HPGDHSD17B10BACE1 | |
| SCHEMBL14965643 | 0.80 | TNF (0.37) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30471775 | 0.79 | ABCG2 (0.43) | BCL2L1ALDH1A1HPGDHSD17B10CHRNB2 | |
| SCHEMBL8356292 | 0.79 | ABCG2 (0.43) | BCL2L1ALDH1A1HPGDHSD17B10CHRNB2 | |
| SCHEMBL28894327 | 0.77 | ABCG2 (0.42) | BCL2L1ALDH1A1HPGDHSD17B10CHRNB2 | |
| SCHEMBL60283 | 0.77 | HDAC4 (0.65) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30605196 | 0.77 | HDAC4 (0.65) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29177819 | 0.77 | ATM (0.44) | USP7ATMMAP4K4NCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0899266-B1 | Process for the production of benzoxazinones | CIBA SC HOLDING AG (CH) | 2003-01-15 | — | — | EP | disclosed |
| US-6040443-A | Process for the production of benzoxazinones | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0899266-A1 | Process for the production of benzoxazinones | Ciba SC Holding AG (CH) | 1999-03-03 | — | — | EP | disclosed |