SCHEMBL14965643

SCHEMBL14965643

c1ccc(-c2cccc(-c3ncncn3)c2-c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
HNF4A P41235 1/20 0.35
ENPP1 P22413 1/20 0.35
ALDH1A1 P00352 4/20 0.34
HSD17B10 Q99714 2/20 0.34
MAPK1 P28482 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
ATM Q13315 1/20 0.34
CYP2A6 P11509 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
NPC1 O15118 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22205201 0.84 TNF (0.39) TNFCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL30471775 0.84 ABCG2 (0.43) TNFCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL8356292 0.84 ABCG2 (0.43) TNFCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL28894327 0.82 ABCG2 (0.42) TNFCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL7024633 0.80 HNF4A (0.43) TNFCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL17313535 0.80 HDAC4 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4HNF4A
SCHEMBL27477978 0.80 ATM (0.41) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL3628549 0.80 CYP2A6 (0.32) ENPP1ALDH1A1HSD17B10MAPK1CYP2A6
SCHEMBL192418 0.78 ALDH1A1 (0.50) TNFHNF4AENPP1ALDH1A1HSD17B10
SCHEMBL13295245 0.77 ATM (0.41) ALDH1A1HSD17B10MAPK1ATMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780409-A1 ORGANIC SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2014-09-24 EP claimed
WO-2013072853-A1 ORGANIC SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2013-05-23 WO claimed