Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513697 | 0.67 | ALDH1A1 (0.39) | TYMSALDH1A1RECQLALOX12L3MBTL1 | |
| SCHEMBL318269 | 0.67 | MEN1 (0.36) | ALDH1A1RECQLALOX12L3MBTL1CA1 | |
| SCHEMBL4228062 | 0.64 | ALDH1A1 (0.42) | TYMSALDH1A1RECQLALOX12L3MBTL1 | |
| SCHEMBL7021814 | 0.63 | ALDH1A1 (0.35) | TYMSALDH1A1RECQLALOX12L3MBTL1 | |
| SCHEMBL12473302 | 0.63 | CES1 (0.32) | ALDH1A1RECQLL3MBTL1MAPK1EHMT2 | |
| SCHEMBL279560 | 0.62 | TYMS (0.62) | TYMSALDH1A1RECQLALOX12L3MBTL1 | |
| SCHEMBL30800362 | 0.62 | TYMS (0.62) | TYMSALDH1A1RECQLALOX12L3MBTL1 | |
| SCHEMBL20401646 | 0.60 | — | — | |
| SCHEMBL12856856 | 0.60 | ALDH1A1 (0.67) | ALDH1A1RECQLALOX12L3MBTL1CA1 | |
| SCHEMBL2538331 | 0.60 | IDO1 (0.38) | ALDH1A1RECQLL3MBTL1MAPK1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863878-B1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA INC (US) | 2003-01-08 | — | — | EP | claimed |
| US-5962469-A | PREVENTION OF OXIDATION TISSUE DAMAGE BY FREE RADICALS | HOECHST MARION ROUSSEL INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-0863878-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997010218-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-20 | — | — | WO | claimed |
| EP-0863878-B1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA INC (US) | 2003-01-08 | — | — | EP | disclosed |