Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.51 |
| ▸ | RXRG | P48443 | 6/20 | 0.51 |
| ▸ | RXRB | P28702 | 5/20 | 0.51 |
| ▸ | RARG | P13631 | 11/20 | 0.46 |
| ▸ | RARB | P10826 | 10/20 | 0.45 |
| ▸ | RARA | P10276 | 8/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024909 | 1.00 | RXRA (0.51) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6876425 | 0.87 | RXRA (0.53) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6879674 | 0.82 | RXRA (0.47) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6870970 | 0.82 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6926719 | 0.82 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6874738 | 0.80 | RXRA (0.67) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6032311 | 0.80 | RXRA (0.67) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6822269 | 0.80 | RXRA (0.67) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6927632 | 0.80 | RXRA (0.44) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6876540 | 0.80 | RXRA (0.47) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832081-B1 | BICYCLIC-AROMATIC COMPOUNDS | GALDERMA RECH DERMATOLOGIQUE (FR) | 2003-01-29 | — | — | EP | claimed |