Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024912 | 1.00 | QPCT (0.33) | QPCTMPOALDH1A1HPGDCYP1A2 | |
| SCHEMBL7020008 | 0.88 | CYP1A2 (0.33) | MPOCYP1A2CRBN | |
| SCHEMBL7020004 | 0.88 | CYP1A2 (0.33) | MPOCYP1A2CRBN | |
| SCHEMBL7012482 | 0.75 | ADORA3 (0.33) | QPCTMPOALDH1A1HPGDCYP1A2 | |
| SCHEMBL7016350 | 0.75 | BRD4 (0.32) | — | |
| SCHEMBL7012478 | 0.75 | ADORA3 (0.33) | QPCTMPOALDH1A1HPGDCYP1A2 | |
| SCHEMBL7016348 | 0.75 | BRD4 (0.32) | — | |
| SCHEMBL7019026 | 0.74 | CYP1A2 (0.32) | CYP1A2CRBN | |
| SCHEMBL7019031 | 0.74 | CYP1A2 (0.32) | CYP1A2CRBN | |
| SCHEMBL7020738 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357114-A1 | Substituted pyrimidin-2,4(1H,3H)-diones as inhibitors of Matrix Metalloproteinases (MMP) | IBFB GmbH Privates Institut für biomedizinische Forschung und Beratung (DE) | 2003-10-29 | — | — | EP | disclosed |