Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 3/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 4/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.33 |
| ▸ | GSK3A | P49840 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pterine SCHEMBL64321 | 0.98 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL5703599 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL27339748 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL906055 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL27566960 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL29287280 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL27866244 | 0.96 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL29205870 | 0.91 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| Pterine SCHEMBL28301534 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL7682920 | 0.73 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688169-A2 | GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS | Lanzatech, Inc. (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20200239896-A1 | GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS | LANZATECH, INC. | 2020-07-30 | — | — | US | disclosed |
| WO-2019068011-A2 | GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS | LANZATECH, INC. (US) | 2019-04-04 | — | — | WO | disclosed |
| US-20160289278-A1 | GENES OF AN OTITIS MEDIA ISOLATE OF NONTYPEABLE HEAMOPHILUS INFLUENZAE | NATIONWIDE CHILDREN'S HOSPITAL | 2016-10-06 | — | — | US | disclosed |
| US-9102729-B2 | Polypeptides from non-typeable Haemophilus influenzae | NOVARTIS VACCINES AND DIAGNOSTICS SRL (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150218231-A1 | GENES OF AN OTITIS MEDIA ISOLATE OF NONTYPEABLE HEAMOPHILUS INFLUENZAE | NATIONWIDE CHILDREN'S HOSPITAL | 2015-08-06 | — | — | US | disclosed |
| US-9034642-B2 | Genes of an otitis media isolate of nontypeable Haemophilus influenzae | NATIONWIDE CHILDREN'S HOSPITAL (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140234363-A1 | POLYPEPTIDES FROM NON-TYPEABLE HAEMOPHILUS INFLUENZAE | NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT) | 2014-08-21 | — | — | US | disclosed |
| US-20140127221-A1 | Genes of an Otitis Media Isolate of Nontypeable Haemophilus Influenzae | NATIONWIDE CHILDREN'S HOSPITAL, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8652773-B2 | Genes of an otitis media isolate of nontypeable Haemophilus influenza | NATIONWIDE CHILDREN'S HOSPITAL, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-7749518-B2 | Viral protein for use in devloping vaccine for treatment and preventon of infection, vision, arthritic and respiratory system disorders | NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT) | 2010-07-06 | — | — | US | disclosed |
| EP-2070945-A1 | Genes of an otitis media isolate of nontypeable haemophilus influenzae | Nationwide Children's Hospital, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20080267966-A1 | Viral protein for use in devloping vaccine for treatment and preventon of infection, vision, arthritic and respiratory system disorders | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2008-10-30 | — | — | US | disclosed |
| US-7390937-B2 | Plants with enhanced levels of nitrogen utilization proteins in their root epidermis and uses thereof | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2008-06-24 | — | — | US | disclosed |
| US-20050131222-A1 | Nucleotide sequence of the haemophilus influenzae Rd genome, fragments thereof, and uses thereof | HUMAN GENOME SCIENCES, INC. (US) | 2005-06-16 | — | — | US | disclosed |
| US-20050044585-A1 | Promoter element exhibits stress inducible expression; fungal nitrate reductases, mutant nitrate reductases lacking post-translational regulation, glutamate synthetase/dehydrogenase, aminotransferases, nitrate transporters, ammonia transporters and amino acid transporters | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2005-02-24 | — | — | US | disclosed |
| US-6846651-B2 | Nucleotide sequence of the Haemophilus influenzae Rd genome, fragments thereof, and uses thereof | HUMAN GENOME SCIENCES, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-6528289-B1 | Isolated polynucleotide; can be used in industrial fermentation and pharmaceutical development | HUMAN GENOME SCIENCES, INC. | 2003-03-04 | — | — | US | disclosed |
| US-6506581-B1 | Nucleotide sequence of the Haemophilus influenzae Rd genome, fragments thereof, and uses thereof | HUMAN GENOME SCIENCE, INC. | 2003-01-14 | — | — | US | disclosed |
| WO-2001055405-A1 | A NOVEL POLYPEPTIDE, A HUMAN MOLYBDENUM PTERIN OXIDE-REDUCTASE 10 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE | BIODOOR GENE TECHNOLOGY LTD. SHANGHAI (CN) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234363-A1 | POLYPEPTIDES FROM NON-TYPEABLE HAEMOPHILUS INFLUENZAE | NGLY1, ANPEP, NT5E | ALDH1A1 4468/4885KDM4E 4817/4885HSD17B10 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.