Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21870608 | 1.00 | CHRM3 (0.38) | CHRM3HTTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL10808055 | 1.00 | CHRM3 (0.38) | CHRM3HTTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL4597568 | 0.94 | HTT (0.35) | CHRM3HTTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL4808864 | 0.94 | HTT (0.35) | CHRM3HTTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL14509636 | 0.84 | KDM4E (0.38) | HTTL3MBTL1KDM4EPNP | |
| SCHEMBL25769664 | 0.83 | TSHR (0.40) | CHRM3HTTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL13839006 | 0.83 | TSHR (0.40) | CHRM3HTTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL10453847 | 0.83 | SLC6A9 (0.41) | CHRM3HTTL3MBTL1PIK3CD | |
| SCHEMBL25663994 | 0.83 | TSHR (0.40) | CHRM3HTTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL19903704 | 0.82 | SPHK1 (0.43) | CHRM3HTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061375-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |