SCHEMBL70250

SCHEMBL70250

CSc1cc(O)cc(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.50
ALDH1A1 P00352 2/20 0.38
CA5A P35218 2/20 0.38
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MCL1 Q07820 1/20 0.37
LCK P06239 1/20 0.36
NOS3 P29474 2/20 0.36
NOS1 P29475 2/20 0.36
ACHE P22303 1/20 0.35
CA12 O43570 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 3/20 0.33
CA14 Q9ULX7 3/20 0.33
LMNA P02545 2/20 0.33
CYP3A4 P08684 2/20 0.33
CA1 P00915 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5179955 0.94 BACE1 (0.41) BACE1ALDH1A1CA5AKDM4ENPC1
SCHEMBL16042161 0.82 CYP3A4 (0.35) BACE1ALDH1A1MCL1NOS3NOS1
SCHEMBL19274301 0.82 BACE1 (0.32) BACE1ALDH1A1MCL1NOS3NOS1
SCHEMBL15934251 0.78 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1TP53RAB9A
SCHEMBL15934304 0.78 TSHR (0.43) ALDH1A1HSD17B10PTGS2ALOX15
SCHEMBL12801845 0.77 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1TP53RAB9A
SCHEMBL2866234 0.75 ALDH1A1 (0.36) ALDH1A1KDM4EMCL1NOS3NOS1
SCHEMBL6068343 0.75 ABL1 (0.58) KDM4ENPC1TP53RAB9ASMN1; SMN2
SCHEMBL8936297 0.73 BACE1 (0.57) BACE1ALDH1A1CA5AKDM4ENPC1
SCHEMBL21602738 0.73 SELL (0.48) ALDH1A1CA5AKDM4ETP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111432-B2 Triangular carbon quantum dots and compositions and uses thereof BEIJING NORMAL UNIVERSITY (CN) 2021-09-07 US claimed
US-20200354630-A1 TRIANGULAR CARBON QUANTUM DOTS AND COMPOSITIONS AND USES THEREOF BEIJING NORMAL UNIVERSITY (CN) 2020-11-12 US claimed
CN-110337482-B Triangular carbon quantum dot and composition and application thereof 北京师范大学 2023-06-02 CN disclosed
US-11111432-B2 Triangular carbon quantum dots and compositions and uses thereof BEIJING NORMAL UNIVERSITY (CN) 2021-09-07 US disclosed
US-11111432-B2 Triangular carbon quantum dots and compositions and uses thereof BEIJING NORMAL UNIVERSITY (CN) 2021-09-07 US disclosed
US-20200354630-A1 TRIANGULAR CARBON QUANTUM DOTS AND COMPOSITIONS AND USES THEREOF BEIJING NORMAL UNIVERSITY (CN) 2020-11-12 US disclosed
US-20200354630-A1 TRIANGULAR CARBON QUANTUM DOTS AND COMPOSITIONS AND USES THEREOF BEIJING NORMAL UNIVERSITY (CN) 2020-11-12 US disclosed
WO-2019134068-A1 TRIANGULAR CARBON QUANTUM DOTS AND COMPOSITIONS AND USES THEREOF BEIJING NORMAL UNIVERSITY (CN) 2019-07-11 WO disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4243674-A HYPOTENSIVE AGENTS; ANALGESICS; ANTISECRETORY AGENTS; ANTIBODY INHIBITORS, AND TRANQUILIZERS PFIZER INC. (US) 1981-01-06 US disclosed
US-4143139-A ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY PFIZER INC. (US) 1979-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 BACE1 4856/4885ALDH1A1 1882/4885CA5A 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.