Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030011 | 0.91 | GPR84 (0.39) | RARBRARARARGGPR84NPC1 | |
| SCHEMBL7024857 | 0.87 | RARB (0.44) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL7029164 | 0.87 | ESR2 (0.41) | RARBRARARARGCYP3A4CYP2C9 | |
| SCHEMBL8027611 | 0.86 | RARB (0.44) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL8027605 | 0.86 | RARB (0.44) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL9763905 | 0.85 | RARB (0.46) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL9764067 | 0.85 | RARB (0.46) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL9763917 | 0.85 | RARB (0.46) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL9764102 | 0.85 | RARB (0.46) | RARBRARARARGCYP3A4CYP2C8 | |
| SCHEMBL9763936 | 0.85 | RARB (0.46) | RARBRARARARGCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |