Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | NAAA | Q02083 | 8/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725555 | 0.94 | ESR2 (0.33) | ESR2NAAAFAAHL3MBTL1 | |
| SCHEMBL7026842 | 0.90 | KDM5A (0.34) | ESR2OPRL1 | |
| SCHEMBL7027057 | 0.89 | FFAR4 (0.33) | ESR2NAAAFAAHCYP2C9 | |
| SCHEMBL7024993 | 0.88 | ESR2 (0.33) | ESR2NAAA | |
| SCHEMBL7031024 | 0.88 | ESR2 (0.35) | ESR2L3MBTL1OPRL1CYP2C9CYP3A4 | |
| SCHEMBL7034715 | 0.88 | KDM5A (0.33) | ESR2OPRL1 | |
| SCHEMBL8390420 | 0.88 | KDM5A (0.33) | ESR2OPRL1 | |
| SCHEMBL8725535 | 0.86 | NAAA (0.35) | NAAAFAAHL3MBTL1CYP2C9ABCB1 | |
| SCHEMBL7031162 | 0.86 | CYP2C9 (0.43) | ESR2NAAAFAAHOPRL1CYP2C9 | |
| SCHEMBL7024343 | 0.86 | NAAA (0.35) | NAAAFAAHL3MBTL1CYP2C9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |