Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025315 | 0.82 | SLC29A1 (0.61) | SLC29A1ADKADORA3ADORA2AADORA1 | |
| SCHEMBL7025980 | 0.82 | SLC29A1 (0.61) | SLC29A1ADKADORA3ADORA2AADORA1 | |
| SCHEMBL7018814 | 0.82 | SLC29A1 (0.61) | SLC29A1ADKADORA3ADORA2AADORA1 | |
| SCHEMBL98801 | 0.78 | SLC29A1 (0.56) | SLC29A1ADORA3ADORA2AADORA1DPP4 | |
| SCHEMBL98800 | 0.78 | SLC29A1 (0.56) | SLC29A1ADORA3ADORA2AADORA1DPP4 | |
| Cordycepin SCHEMBL23735980 | 0.77 | ADORA3 (0.63) | SLC29A1ADORA3ADORA2AADORA1DPP4 | |
| Cordycepin SCHEMBL21562220 | 0.77 | ADORA3 (0.63) | SLC29A1ADORA3ADORA2AADORA1DPP4 | |
| Cordycepin SCHEMBL20419244 | 0.77 | ADORA3 (0.63) | SLC29A1ADORA3ADORA2AADORA1DPP4 | |
| SCHEMBL24538657 | 0.77 | SLC29A1 (0.55) | SLC29A1ADORA3ADORA2AADORA1DPP4 | |
| Cordycepin SCHEMBL21591024 | 0.77 | ADORA3 (0.63) | SLC29A1ADORA3ADORA2AADORA1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002018404-A9 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | HOFFMANN LA ROCHE (CH) | 2003-10-02 | — | — | WO | claimed |
| WO-2002018404-A9 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | HOFFMANN LA ROCHE (CH) | 2003-10-02 | — | — | WO | disclosed |
| EP-1315736-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002018404-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | disclosed |