Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65267 | 0.96 | ELANE (0.40) | ELANEPRKCAALDH1A1TSHRDGAT1 | |
| Ammonia Solution, Strong SCHEMBL25421893 | 0.93 | ELANE (0.39) | ELANEPRKCAALDH1A1TSHRDGAT1 | |
| SCHEMBL22362392 | 0.90 | ELANE (0.37) | ELANEPRKCAALDH1A1TSHRDGAT1 | |
| Formic Acid SCHEMBL29279052 | 0.84 | ELANE (0.34) | ELANEPRKCA | |
| SCHEMBL21831923 | 0.84 | ALDH1A1 (0.50) | ELANEPRKCAALDH1A1TSHR | |
| Methylene Chloride SCHEMBL28156559 | 0.84 | ELANE (0.35) | ELANEPRKCA | |
| SCHEMBL15743144 | 0.83 | ELANE (0.37) | ELANEPRKCAALDH1A1TSHRDGAT1 | |
| SCHEMBL1537712 | 0.83 | ELANE (0.37) | ELANEPRKCAALDH1A1TSHRDGAT1 | |
| SCHEMBL20867951 | 0.82 | ELANE (0.33) | ELANEPRKCA | |
| SCHEMBL11550953 | 0.82 | ELANE (0.33) | ELANEPRKCAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274674-A1 | CHOLINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Universita' Degli Studi Di Roma "La Sapienza" (IT) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001081296-A1 | CHOLINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | UNIVERSITA' DEGLI STUDI DI ROMA 'LA SAPIENZA' (IT) | 2001-11-01 | — | — | WO | disclosed |