Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL2001932 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL27387403 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL28208503 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL2356114 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL15647218 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL8470548 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL30153094 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL30533447 | 0.91 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL9631840 | 0.91 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1TSHRMEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL63150 | 0.87 | CA1 (0.44) | ALDH1A1TSHRMEN1KMT2AGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605421-A | Spiro-2, 3-dihydroquinoline-4-ketone-3, 4-dihydrocoumarin bioactive skeleton and synthesis method and application thereof | 山东瀚华工程设计有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114539252-A | 2, 3-dihydroquinoline-4-ketone bioactive skeleton and synthesis method and application thereof | 山东瀚华工程设计有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20030055297-A1 | An alkyl, cycloalkyl, arylalkyl dihydroxy compound useful as intermediates; a cost-effective preparation | ABBOTT LABORATORIES | 2003-03-20 | — | — | US | disclosed |
| WO-2002081441-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRROLIDINE NEURAMINIDASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055297-A1 | An alkyl, cycloalkyl, arylalkyl dihydroxy compound useful as intermediates; a cost-effective preparation | NEU4, NEU2, NEU1 | ALDH1A1 410/4885L3MBTL1 3915/4885TSHR 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.