SCHEMBL702717

SCHEMBL702717

CCCCCCCCCCCCCCCCOCC(CO)OCCCCC(O)CO

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.65
PLA2G2C Q5R387 1/20 0.53
LPAR1 Q92633 4/20 0.50
LPAR3 Q9UBY5 4/20 0.50
HTT P42858 1/20 0.50
LPAR2 Q9HBW0 1/20 0.50
ALDH1A1 P00352 1/20 0.45
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
TLR2 O60603 5/20 0.45
LPAR5 Q9H1C0 1/20 0.44
SPHK1 Q9NYA1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12888559 0.92 USP2 (0.62) USP2PLA2G2CLPAR1LPAR3HTT
SCHEMBL19257793 0.89 USP2 (0.67) USP2PLA2G2CLPAR1LPAR3HTT
SCHEMBL7063456 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2
SCHEMBL7060157 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2
SCHEMBL7058701 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2
SCHEMBL25266425 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2
SCHEMBL103054 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2
SCHEMBL10561321 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2
SCHEMBL2417250 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2
SCHEMBL7063486 0.88 USP2 (0.63) USP2LPAR1LPAR3HTTLPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9968622-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2018-05-15 US disclosed
US-9968622-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2018-05-15 US disclosed
US-20170246197-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-08-31 US disclosed
US-20170246197-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-08-31 US disclosed
US-9566288-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-02-14 US disclosed
US-9566288-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-02-14 US disclosed
EP-2604614-B1 Oxidized phospholipids VASCULAR BIOGENICS LTD (IL) 2016-03-09 EP disclosed
EP-2604614-B1 Oxidized phospholipids VASCULAR BIOGENICS LTD (IL) 2016-03-09 EP disclosed
US-20150216882-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-08-06 US disclosed
US-20150216882-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-08-06 US disclosed
US-20120130108-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2012-05-24 US disclosed
US-8124800-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2012-02-28 US disclosed
US-8124800-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2012-02-28 US disclosed
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2010-12-16 US disclosed
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2010-12-16 US disclosed
US-7807847-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2010-10-05 US disclosed
US-7807847-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2010-10-05 US disclosed
WO-2008084472-A2 IMPROVED PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS VASCULAR BIOGENICS LTD. (IL) 2008-07-17 WO disclosed
US-20070112211-A1 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2007-05-17 US disclosed
US-20070112211-A1 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317881-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS PHOSPHO1, SGMS1, SGMS2 USP2 4230/4885PLA2G2C 19/4885LPAR1 199/4885
US-20150216882-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 USP2 4148/4885PLA2G2C 13/4885LPAR1 71/4885
US-20170246197-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 USP2 4148/4885PLA2G2C 13/4885LPAR1 71/4885
US-20120130108-A1 PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS PHOSPHO1, SGMS1, SGMS2 USP2 4230/4885PLA2G2C 19/4885LPAR1 199/4885
US-20070112211-A1 Process for the preparation of oxidized phospholipids PHOSPHO1, SGMS1, SGMS2 USP2 4230/4885PLA2G2C 19/4885LPAR1 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.