Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027272 | 1.00 | LMNA (0.64) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL272915 | 0.81 | ADORA2A (0.68) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL13403870 | 0.81 | ADORA2A (0.68) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL13437799 | 0.81 | ADORA2A (0.68) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL24359132 | 0.81 | LMNA (0.78) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL22559823 | 0.81 | LMNA (0.78) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL114917 | 0.81 | LMNA (0.78) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL16579288 | 0.81 | LMNA (0.78) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL440329 | 0.81 | LMNA (0.78) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL10176676 | 0.81 | LMNA (0.78) | LMNANT5EHIF1AADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002018404-A9 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | HOFFMANN LA ROCHE (CH) | 2003-10-02 | — | — | WO | claimed |
| EP-1315736-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | claimed |
| WO-2002018404-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | claimed |