SCHEMBL7027733

SCHEMBL7027733

C[Si](C)=[Ti](C1=CC=CC1)c1cccc2c1Cc1ccccc1-2.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.34
RAB9A P51151 2/20 0.31
NPC1 O15118 1/20 0.31
APAF1 O14727 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
CASP1 P29466 1/20 0.30
BLM P54132 1/20 0.30
CASP7 P55210 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6272386 0.92 PNMT (0.36) PNMTRAB9ANPC1
SCHEMBL7025953 0.87 PNMT (0.44) PNMTRAB9ANPC1APAF1ALDH1A1
SCHEMBL7035302 0.84 PNMT (0.35) PNMTRAB9ANPC1APAF1ALDH1A1
SCHEMBL7028986 0.83 PNMT (0.35) PNMTRAB9ANPC1APAF1ALDH1A1
SCHEMBL7634976 0.82 PNMT (0.34) PNMTRAB9ANPC1APAF1ALDH1A1
SCHEMBL7028960 0.73 PNMT (0.42) PNMTRAB9ANPC1APAF1ALDH1A1
SCHEMBL7029454 0.73 PNMT (0.44) PNMTRAB9ANPC1APAF1ALDH1A1
SCHEMBL8169457 0.72 PNMT (0.36) PNMTRAB9ANPC1
SCHEMBL6675328 0.72 PNMT (0.36) PNMTRAB9ANPC1
SCHEMBL6271159 0.72 NPC1 (0.41) PNMTRAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811628-B1 METHYLALUMINO-OXY COMPOUNDS AND CATALYSTS FOR THE PREPARATION O POLYMERS CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO (JP) 2003-03-05 EP disclosed
US-6277934-B1 A SYNDIOTACTIC HOMO- OR COPOLYMER FROM A STYRENIC COMPOUND IN THE PRESENCE OF A METALLOCENE OF HIGH, STABLE ACTIVITY COMPRISING A TITANIUM COMPOUND AND AN ORGANIC ALUMINOXY COMPOUND OF SPECIFIC NUCLEAR MAGNETIC RESONANCE SPECTRUM IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6034191-A Organic aluminoxy compound and catalyst for producing polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-03-07 US disclosed
US-5917073-A Organic aluminoxy compound and catalyst for producing polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-06-29 US disclosed
EP-0811628-A1 ORGANIC ALUMINO-OXY COMPOUNDS AND CATALYSTS FOR THE PREPARATION O POLYMERS CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-12-10 EP disclosed